4-PrO-MET
Pharmaceutical compound
Nº Q137800936 ★★
Uncommon · Knowledge
4-PrO-MET
Pharmaceutical compound
4-PrO-MET, also known as 4-propionyloxy-N-methyl-N-ethyltryptamine or as O-propionyl-4-HO-MET, is a psychedelic drug of the tryptamine and 4-hydroxytryptamine families related to 4-AcO-DMT (psilacetin). It is thought to be a prodrug of 4-HO-MET (metocin) similarly to 4-AcO-MET (metacetin).
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From Wikipedia
4-PrO-MET, also known as 4-propionyloxy-N-methyl-N-ethyltryptamine or as O-propionyl-4-HO-MET, is a psychedelic drug of the tryptamine and 4-hydroxytryptamine families related to 4-AcO-DMT (psilacetin). It is thought to be a prodrug of 4-HO-MET (metocin) similarly to 4-AcO-MET (metacetin). 4-PrO-MET was encountered online as a novel designer drug in August or September 2025. It is anecdotally claimed to produce more intense psychedelic visuals than psilocin (4-HO-DMT) but to be "less heavy" and to have good tolerability. 4-PrO-MET is not an explicitly controlled substance in the United States or in Canada.
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