Diazinon

Diazinon (IUPAC name: O,O-Diethyl O-[4-methyl-6-(propan-2-yl)pyrimidin-2-yl] phosphorothioate, INN - Dimpylate), a colorless to dark brown liquid, is a thiophosphoric acid ester developed in 1952 by Ciba-Geigy, a Swiss chemical company (later Novartis and then Syngenta). It is a nonsystemic organophosphate insecticide formerly used to control cockroaches, silverfish, ants, and fleas in residential, non-food buildings. Diazinon was heavily used during the 1970s and early 1980s for general-purpose gardening use and indoor pest control. A bait form was used to control scavenger wasps in the western U.S. Diazinon is used in flea collars for domestic pets in Australia and New Zealand. Diazinon is a major component in the "Golden Fleece" brand sheep dip. Residential uses of diazinon were outlawed in the U.S. in 2004 because of human health risks but it is still approved for agricultural uses. An emergency antidote is atropine. Routes of contact for diazinon include breathing, consuming, or contact with skin. Negative health effects from contact with diazinon include epiphora, drool or rhinorrhea, loss of appetite, vomiting, intense coughing, abdominal pain, headaches or muscle stiffness. Some other physiological effects include pinpoint pupils, increased heart rate, seizures, or coma. While diazinon has many different health risks, the US Agency for Toxic Substances and Disease Registry has not categorized it as a carcinogen.