Common · History
Epigenetic clock
Biochemical test
An epigenetic clock is an analytical method used as a biomarker of aging to estimate "biological age." The method relies on age-related modifications to DNA that occur over time and regulate how genes are expressed.
From Wikipedia
An epigenetic clock is an analytical method used as a biomarker of aging to estimate "biological age." The method relies on age-related modifications to DNA that occur over time and regulate how genes are expressed. Many epigenetic clocks are based on the analysis of DNA methylation, measuring the accumulation of methyl groups to CpG regions of DNA molecules. More recently, new epigenetic clocks have been developed based on the histone code, chromatin accessibility and nucleosome positioning.
Text: Wikipédia, CC BY-SA 4.0. · Image: Mariuswalter (CC BY-SA 4.0) ·
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DNA methylation
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine
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ATAC-seq
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Comparative genomic hybridization
Method to evaluate biological samples
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Histone methylation
The modification of histones by addition of methyl groups.
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Epigenetics
Study of changes in gene expression or cellular phenotype
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Cytogenetics
Branch of genetics