Fazamorexant
Orexin receptor antagonist
Nº Q131177082 ★★★
Rare · Knowledge
Fazamorexant
Orexin receptor antagonist
Fazamorexant (INNTooltip International Nonproprietary Name), sold under the brand name Mengping, is an orexin receptor antagonist which is used in the treatment of insomnia in China. It is taken orally.
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From Wikipedia
Fazamorexant (INNTooltip International Nonproprietary Name), sold under the brand name Mengping, is an orexin receptor antagonist which is used in the treatment of insomnia in China. It is taken orally. The drug acts as a dual orexin receptor antagonist (DORA), or as an antagonist of both the orexin OX1 and OX2 receptors. Its time to peak levels is 0.6 to 1.3 hours and its elimination half-life is 1.9 to 3.7 hours. Fazamorexant was developed by Jiangsu Yangtze River Pharmaceutical Group and/or Shanghai Haiyan Pharmaceutical Technology in China. Relatively little public information is available on fazamorexant. This was such that it had to be excluded from a 2020 literature review of orexin receptor antagonists for insomnia. The drug was approved in China in May 2026.
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