Keratoconus

Keratoconus is an eye disorder in which the cornea, the transparent front part of the eye, gradually thins and bulges outward into a cone shape. This causes distorted vision, including blurry vision, double vision, increased nearsightedness, irregular astigmatism, and light sensitivity, which can reduce quality of life. Both eyes are usually affected. The cause is not fully understood but likely involves a combination of genetic, environmental, and hormonal factors. Having a parent, sibling, or child with keratoconus increases risk significantly. Environmental risk factors include frequent eye rubbing and allergies. Diagnosis is typically made with corneal topography, which maps the shape of the cornea and reveals characteristic changes. In early stages, vision is often corrected with glasses or soft contact lenses. As the condition progresses, rigid or scleral contact lenses may be needed. In 2016, the FDA approved corneal collagen cross-linking to halt progression. If vision cannot be improved with contact lenses and the cornea becomes too thin or scarred, a corneal transplant may be necessary. Keratoconus affects about 1 in 2,000 people, though some estimates suggest it may be as common as 1 in 400. It typically develops in late childhood or early adulthood and occurs in all populations, though it may be more common in some ethnic groups, such as people of Asian descent. The name comes from the Greek kéras (cornea) and Latin cōnus (cone).