Propanidid

Chemical compound

Propanidid is an ultra short-acting phenylacetate general anesthetic. It was originally introduced by Bayer in 1963 but anaphylactic reactions caused it to be withdrawn shortly afterwards. The cause of the anaphylaxis has not been determined.

Nº Q409719 ★

Common · Knowledge

Propanidid

Chemical compound

Propanidid is an ultra short-acting phenylacetate general anesthetic. It was originally introduced by Bayer in 1963 but anaphylactic reactions caused it to be withdrawn shortly afterwards. The cause of the anaphylaxis has not been determined.

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From Wikipedia

Propanidid is an ultra short-acting phenylacetate general anesthetic. It was originally introduced by Bayer in 1963 but anaphylactic reactions caused it to be withdrawn shortly afterwards. The cause of the anaphylaxis has not been determined. Similar to Althesin, Cremophor EL was used as part of the formulation for propanidid. Cremephor EL has been shown to cause anaphylactic reactions in humans in several cases (both when given intravenously and orally), and several negative reactions have been recorded for drugs using Cremephor EL. However, some have argued that the anaphylaxis was a reaction to propanidid itself.

Text: Wikipédia, CC BY-SA 4.0. · Image: User:Innerstream (Public domain) ·

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