Typhus

Typhus, also known as typhus fever, is a group of infectious diseases that include epidemic typhus, scrub typhus, and murine typhus. Common symptoms such as fever, headache, and a rash typically begin one to two weeks after exposure. The diseases are caused by specific types of bacterial infection. Epidemic typhus is caused by Rickettsia prowazekii spread by body lice, scrub typhus is caused by Orientia tsutsugamushi spread by chiggers, and murine typhus is caused by Rickettsia typhi spread by fleas. Vaccines have been developed, but none are commercially available. Prevention is achieved by reducing exposure to the organisms that spread the disease. Treatment is with the antibiotic doxycycline. Epidemic typhus generally occurs in outbreaks when poor sanitary conditions and crowding are present. While once common, it is now rare. Scrub typhus occurs in Southeast Asia, Japan, and northern Australia. Murine typhus occurs in tropical and subtropical areas of the world. Typhus has been described since at least 1528. The name comes from the Greek tûphos (τῦφος), meaning 'hazy' or 'smoky' and commonly used as a word for delusion, describing the state of mind of those infected. While typhoid means 'typhus-like', typhus and typhoid fever are distinct diseases caused by different types of bacteria, the latter by specific strains of Salmonella typhi. However, in some languages such as German, the term typhus does mean 'typhoid fever', and the here-described typhus is called by another name, such as the language's equivalent of 'spotted fever'.