Caseous lymphadenitis

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Caseous lymphadenitis (CLA) is an infectious disease caused by the bacterium Corynebacterium pseudotuberculosis, that affects the lymphatic system, resulting in abscesses in the lymph nodes and internal organs. It is found mostly in goats and sheep and at the moment it has no cure. This disease is widely distributed throughout the world. It is found in North and South America, Australia, New Zealand, Europe, Asia and Africa. Caseous lymphadenitis causes considerable economic harm, because skins and carcasses have to be condemned. It seriously affects reproduction efficiency, wool, meat and milk production. Particularly in Australia, one of the largest producers of meat and wool. Studies have found CL incidence in commercial goat herds as high as 30%. The causative organism of caseous lymphadenitis is Corynebacterium pseudotuberculosis. Once successfully established within the host, this pathogen will circumvent the immune system with ease.