Cholera toxin

Protein complex secreted by the bacterium Vibrio cholerae

Cholera toxin (also known as choleragen, CTX, CTx and CT) is a potent enterotoxin produced by the bacterium Vibrio cholerae which causes severe watery diarrhea and dehydration that define cholera infections. The toxin is a member of the heat-labile enterotoxin family, and exists as an AB5 multimeric toxin with one enzymatically-active A subunit and five receptor-binding B subunits that facilitate host cell entry.