Urapidil

Médicament hypotenseur sympatholytique

Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist.

Nº Q418922 ★★

Peu commune · Savoirs

Urapidil

Médicament hypotenseur sympatholytique

Texte en anglais

Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist.

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Médiane 7 j

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Ventes 30 j

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Fourchette 30 j

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Dernière vente
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Moyenne 30 j
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Plus bas 30 j
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Plus haut 30 j
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Ventes 7 j
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Sur Wikipédia

Texte en anglais Pas encore d'article dans ta langue : extrait en anglais.

Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist. Although an initial report suggested that urapidil was also an α2-adrenoceptor agonist, this was not substantiated in later studies that demonstrated it was devoid of agonist actions in the dog saphenous vein and the guinea-pig ileum. Unlike some other α1-adrenoceptor antagonists, urapidil does not elicit reflex tachycardia, and this may be related to its weak β1-adrenoceptor antagonist activity, as well as its effect on cardiac vagal drive. Urapidil is currently not approved by the U.S. Food and Drug Administration, but it is available in Europe.

Texte : Wikipédia en anglais, CC BY-SA 4.0. · Image : AlyInWikiWonderland (CC0) ·

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