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Aflibercept

Pharmaceutical drug

Texto em inglês

Aflibercept, sold under the brand names Eylea and Zaltrap among others, is a medication used to treat wet macular degeneration and metastatic colorectal cancer. It was developed by Regeneron Pharmaceuticals. It is an inhibitor of vascular endothelial growth factor (VEGF).

Na Wikipédia

Texto em inglês Ainda não há artigo no seu idioma: trecho em inglês.

Aflibercept, sold under the brand names Eylea and Zaltrap among others, is a medication used to treat wet macular degeneration and metastatic colorectal cancer. It was developed by Regeneron Pharmaceuticals. It is an inhibitor of vascular endothelial growth factor (VEGF). Aflibercept is a recombinant fusion protein consisting of the extracellular domains of human VEGF receptor 1 and 2 fused to the Fc portion of human IgG1. By acting as a soluble decoy for the natural VEGF receptors, aflibercept inhibits their activation, thereby reducing angiogenesis.

Texto: Wikipédia em inglês, CC BY-SA 4.0. · Imagem: Sławomir Liberski, Małgorzata Wichrowska, Jarosław Kocięcki;... (Public domain) ·

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