Histone methylation
The modification of histones by addition of methyl groups.
Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double helix wraps around to form chromosomes. Methylation of histones can either increase or decrease transcription of genes, depending on which amino acids in the histones are methylated, and how many methyl groups are attached.
Nº Q4117777 ★★
Incomum · História
Histone methylation
The modification of histones by addition of methyl groups.
Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double helix wraps around to form chromosomes. Methylation of histones can either increase or decrease transcription of genes, depending on which amino acids in the histones are methylated, and how many methyl groups are attached.
Na Wikipédia
Texto em inglês Ainda não há artigo no seu idioma: trecho em inglês.
Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double helix wraps around to form chromosomes. Methylation of histones can either increase or decrease transcription of genes, depending on which amino acids in the histones are methylated, and how many methyl groups are attached. Methylation events that weaken chemical attractions between histone tails and DNA increase transcription because they enable the DNA to uncoil from nucleosomes so that transcription factor proteins and RNA polymerase can access the DNA. This process is critical for the regulation of gene expression that allows different cells to express different genes.
Texto: Wikipédia em inglês, CC BY-SA 4.0. ·
Cartas próximas
-
Metilação do ADN
Nº Q874745 ★★
Sem ofertas
-
Histona
Nº Q36293 ★★
Sem ofertas
-
KMT2A
Gene da espécie Homo sapiens
Nº Q18029164 ★★
Sem ofertas
-
Histona desacetilase
Nº Q174378 ★
Sem ofertas
-
Nucleossoma
Nº Q271794 ★
Sem ofertas
-
Cromatina
Complexo de DNA e proteínas em células eucarióticas
Nº Q180951 ★★★
Sem ofertas