MELAS syndrome
One of the family of mitochondrial cytopathies, which also include MERRF, and Leber's hereditary optic neuropathy
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MELAS syndrome
One of the family of mitochondrial cytopathies, which also include MERRF, and Leber's hereditary optic neuropathy
MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like episodes) is one of the family of mitochondrial diseases, which also include MIDD (maternally inherited diabetes and deafness), MERRF syndrome, and Leber's hereditary optic neuropathy. It was first characterized under this name in 1984.
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MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like episodes) is one of the family of mitochondrial diseases, which also include MIDD (maternally inherited diabetes and deafness), MERRF syndrome, and Leber's hereditary optic neuropathy. It was first characterized under this name in 1984. A feature of these diseases is that they are caused by defects in the mitochondrial genome which is inherited purely from the female parent. The most common MELAS mutation is one in mitochondrial DNA (mtDNA) referred to as m.3243A>G.
Texto: Wikipédia em inglês, CC BY-SA 4.0. · Imagem: Abu-Amero KK, Al-Dhalaan H, Bohlega S, Hellani A, Taylor RW. (CC BY 2.0) ·
