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Tandem repeat
DNA where one or more nucleotides are repeated and the repetitions are directly adjacent
In genetics, tandem repeats occur in DNA when a pattern of one or more nucleotides is repeated and the repetitions are directly adjacent to each other, e.g. ATTCG ATTCG ATTCG, in which the sequence ATTCG is repeated three times. Several protein domains also form tandem repeats within their amino acid primary structure, such as armadillo repeats.
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Texto em inglês Ainda não há artigo no seu idioma: trecho em inglês.
In genetics, tandem repeats occur in DNA when a pattern of one or more nucleotides is repeated and the repetitions are directly adjacent to each other, e.g. ATTCG ATTCG ATTCG, in which the sequence ATTCG is repeated three times. Several protein domains also form tandem repeats within their amino acid primary structure, such as armadillo repeats. However, in proteins, perfect tandem repeats are rare in naturally occurring proteins, but they have been added to designed proteins. Tandem repeats constitute about 8% of the human genome. They are implicated in more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington's disease, and several cancers.
Texto: Wikipédia em inglês, CC BY-SA 4.0. ·
