Dimetindene
Chemical compound
Nº Q426070 ★★★
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Dimetindene
Chemical compound
Dimetindene, also sold under the brand name Fenistil, is an antihistamine/anticholinergic. It is a first generation selective H1 antagonist. Dimetindene is an atypical first generation H1 antagonist as it only minimally passes across the blood–brain barrier, and has no sedating effect after a single dose.
Último precio
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Precio mínimo
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Mediana 7 d
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Ventas 30 d
0
Rango 30 d
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En circulación
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mediana
mín – máx
ventas
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- Media 30 d
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- Mínimo 30 d
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- Máximo 30 d
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- Ventas 7 d
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- Ventas 30 d
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En Wikipedia
Texto en inglés Aún no hay artículo en tu idioma: extracto en inglés.
Dimetindene, also sold under the brand name Fenistil, is an antihistamine/anticholinergic. It is a first generation selective H1 antagonist. Dimetindene is an atypical first generation H1 antagonist as it only minimally passes across the blood–brain barrier, and has no sedating effect after a single dose. (S)-(+)-dimetindene is also a strong M2 receptor antagonist, with this enantiomer being more potent (up to 41-fold) for all muscarinic receptors assayed. The (R)-(-)-enantiomer is the eutomer regarding the H1 receptor ((R)-isomer pA2 = 9.42; (S)-isomer pA2 = 7.48). It was patented in 1958 and came into medical use in 1960.
Texto: Wikipedia en inglés, CC BY-SA 4.0. · Imagen: Fvasconcellos 15:30, 15 July 2007 (UTC) (Public domain) ·
